The Fold Variant BM4 Is Beneficial in a Therapeutic Bet v 1 Mouse Model
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چکیده
منابع مشابه
The Fold Variant BM4 Is Beneficial in a Therapeutic Bet v 1 Mouse Model
BACKGROUND Specific immunotherapy using recombinant allergens is clinically effective; still wild-type allergens can provoke treatment-induced side effects and often show poor immunogenicity in vivo. Thus, we tested the low IgE-binding, highly immunogenic fold variant BM4 in a Bet v 1 mouse model. METHODS Recombinant BM4 was used as active vaccine ingredient to treat mice sensitized to Bet v ...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2013
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2013/832404